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Comparison of FibroTest and liver biopsy

Вверх на рівень

Biopsy is a medical procedure which consists of taking a liver sample using an adapted needle for analyzing it under the microscope.

FibroTest is a diagnostic tool based on a simple blood test.

Biopsy is an imperfect diagnostic tool and has a mean error of 30%.
It is not without risk or pain: 1 patient out of 3 complains of pain, 6 out of 1,000 have severe complications and regrettably, death occurs for 3 patients per 10,000 biopsies, which is unacceptable for a diagnosis.

FibroTest is a simple blood test which has the same relevance as a 25 mm biopsy.

Liver biopsy FibroTest / FibroMax
  • pain: 30% of patients
  • severe complications: 6 out of 1,000
  • death: 3 per 10,000
  • no risk
  • hospitalization
  • simple blood test
  • at your usual laboratory
  • variable result (according to the center and the physician)
  • consistent results: accuracy of a blood test - reproducibility greater than 95%
  • significant risk of error if the biopsy is too small
  • result equivalent to a 25 mm biopsy
  • difficult to repeat for the medical follow-up
  • very easy to repeat (blood test)
  • unfeasible by intercostal route if coagulation disorder, ascites
  • contraindicated if severe respiratory insufficiency
  • unapplicable if acute hepatitis, extrahepatic cholestasis, severe hemolysis, Gilbert's syndrome with high unconjugated hyperbilirubinemia
  • in cases of acute inflammatory syndrome, just postpone blood test
  • unfavorable risk/benefit ratio
  • excellent risk/benefit ratio
  • enables other problems associated with fibrosis to be dtected, such as activity or steatosis
  • our FibroMax test enables these diagnoses to be made with the same blood test: activity (ActiTest) and steatosis (SteatoTest).

The benefit/risk ratio of biopsy is not suitable for the diagnoses of the most common liver diseases. Biopsy remains useful as a second-line tool in cases where the FibroTest are not applicable or in rare liver diseases or complexes.

In conclusion, FibroTest has the same diagnostic value as a 25 mm biopsy, using a simple blood test, without pain and without risk, and can be easily repeated by the physician if necessary.

The complete list of publications is available on the website : liste des publications.

Welcome to BioPredictive

Non-invasive liver diagnostic tests.

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BioPredictive
40 rue du Bac
75007 Paris
FRANCE

Tel : +33 1 45 44 30 64
email : contact@biopredictive.com


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